A study of alanine aminotransferase - aspartate aminotransferase as a marker of advanced alcoholic liver disease
نویسندگان
چکیده
منابع مشابه
Optimization of methods for aspartate aminotransferase and alanine aminotransferase.
Conditions for accurate measurement of catalytic activity of aspartate aminotransferase and alanine aminotransferase in human serum have been reinvestigated. The basic variables (kind of buffer, buffer concentration, pH, ion effects, and the influence of pyridoxal-5-phosphate) can now be considered optimized. On this basis, the kinetic parameters of both aminotransferases were determined, i.e.,...
متن کاملalanine aminotransferase elevation in obese infants and children: a marker of early onset non alcoholic fatty liver disease
conclusions elevation of liver enzymes appears in 29 % obese children in a tertiary care centre. absolute alanine aminotransferase levels are significantly higher in obese than in overweight children. even obese children with normal liver enzymes show signs of fatty liver disease as demonstrated by liver enzymes at the upper limit of normal. results elevated alanine aminotransferase was observe...
متن کاملCorrelation of serum alanine aminotransferase and aspartate aminotransferase with coronary heart disease.
OBJECTIVE This study aimed to explore the relationship between different risk factors (especially serum alanine aminotransferase [ALT] and aspartate aminotransferase [AST]) and coronary heart disease (CHD). METHODS A total of 610 inpatients were recruited. Initial coronary angiography (CAG) was performed to evaluate the severity of coronary lesions. On the basis of findings from CAG, patients...
متن کاملAlanine Aminotransferase Elevation in Obese Infants and Children: A Marker of Early Onset Non Alcoholic Fatty Liver Disease
BACKGROUND Elevated aminotransferases serve as surrogate markers of non-alcoholic fatty liver disease, a feature commonly associated with the metabolic syndrome. Studies on the prevalence of fatty liver disease in obese children comprise small patient samples or focus on those patients with liver enzyme elevation. OBJECTIVES We have prospectively analyzed liver enzymes in all overweight and o...
متن کاملThe value of aspartate aminotransferase and alanine aminotransferase in cardiovascular disease risk assessment
OBJECTIVE Aspartate aminotransferase to alanine aminotransferase (AST/ALT) ratio, reflecting liver disease severity, has been associated with increased risk of cardiovascular disease (CVD). The aim of this study was to evaluate whether the AST/ALT ratio improves established risk prediction tools in a primary care population. METHODS Data were analysed from a prospective cohort of 29 316 UK pr...
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ژورنال
عنوان ژورنال: International Journal of Advances in Medicine
سال: 2020
ISSN: 2349-3933,2349-3925
DOI: 10.18203/2349-3933.ijam20201028